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(11)    Patent No :    AP 2728   
(21)    Application No :    AP/P/2011/005616   
(22)    Filing Date :    17.08.2009   
(24)    Date of Grant &    28.08.2013   
           
(45)    Publication :

(30)    Priority Data

(33) Country    (31) Number    (32) Date
US            61/092,470        28.08.2008
US            61/227,212        21.07.2009
           
(84)  Designated State           
BW    GM    GH    KE    LS    LR    MW  MZ  NA
SL    SD    SZ    TZ    UG    ZM    ZW
(73) Applicant(s)

PFIZER INC., 235 East 42nd Street, New York, New York 10017,
United States of America
(72) Inventors

COLLMAN Benjamin Micah, United States of

America

MASCITTI Vincent, United States of America

(74) Representative

GALLOWAY & COMPANY

ZIMBABWE
(51)  International  Classification   C07D 493/10 (2006.01)    C07H 15/18 (2006.01)
A61K 31/357 (2006.01)   
(54)    Title

Dioxa-bicyclo[3.2.1.] octane-2,3,4-triol derivatives

(57)    Abstract

Compounds of Formula (I) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by
sodium-glucose transporter inhibitors (in particular, SGLT2 inhibitors). The compounds disclosed herein are useful for the prevention and treatment of obesity and its associated co-morbidities, in particular type II (type 2) diabetes.

(56)    Documents Cited :    WO 2008/013280 A    EP 1 852 439 A    WO 2007/140191 A

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