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(11)    Patent No :    AP 2671   
(21)    Application No :    AP/P/2006/003773   
(22)    Filing Date :    27.05.2005   
(24)    Date of Grant &    23.05.2013   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
IN    0969DEL2004    27.05.2004
(84)    Designated State

BW    GM    GH    KE    LS    MW  MZ   NA   SL
SD    SZ    T Z    UG    ZM    ZW
(73) Applicant(s)

COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH, Intellectual Property Management Division, Niscair Building,

3rd Floor, 14 Satsang Vihar Marg, Special Institutional India
(72) Inventors

RATHOD Meena Rajnikant, India

SHETHIA Bhupendra Dhanvantrai, India

PANDYA Jayant Batukrai, India

et al

(74) Representative

HONEY & BLANCKENBERG
 

(51)  International  Classification   A61P31/06 (2006.01)    A61K 35/78 (2006.01)
(54)    Title

Enhancement of antitubercular activity of extracts of salicornia brachiata

(57)    Abstract

The present invention relates to enhancement of anti-tubercular activity of active fraction isolated from Salicornia brachiata. The invention also discloses the non-toxic nature of the fraction and positively identifies sucrose as its main constituent Pure sucrose is shown to have no anti-tubercular activity indicating thereby that activity of the fraction resides in one or more of the minor constituents. The minor constituents are shown to be relatively low molecular weight entities and a chromatographic technique is disclosed for separating them from the bulk sucrose to probe their activities and structures in detail, as also the possibility of their synthesis if the leads thrown up are novel.

(56)    Documents Cited :    DATABASE WPI    DAVE SHWETA P et al    BHOSALE S H et al    FR 2 657 011 A    DE 196

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