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(11)    Patent No :    AP 2651    (73) Applicant(s)       
(21)    Application No :    AP/P/2010/005390    NATCO PHARMA LIMITED, Natco House, Road No. 2,       
            Banjara Hills, Hyderabad 500 033, Andhra Pradesh,       
                   
(22)    Filing Date :    02.03.2009    India       
(24)    Date of Grant &    25.04.2013           
                   
(45)    Publication :

(30)  Priority Data    (72) Inventors

    (33) Country    (31) Number    (32) Date    ADIBHATLA KALISATYA Bhujanga Rao, India   
    US            12/042,235        04.03.2008    KOMPELLA Amala Kishan, India   
    US            12/042,247        04.03.2008       
                            (74) Representative   
(84)    Designated State                   
    BW    GM    GH    KE    LS    MW    MZ   NA   SL    GALLOWAY & COMPANY   
    SD    SZ    T Z    UG    ZM    ZW        ZIMBABWE       
                                       
(51)    International    Classification    C07D 401/04 (2006.01)    A61P 35/02 (2006.01)   
                            A61K 31/506 (2006.01)   
(54)    Title

Crystal form of phenylamino pyrimidine derivatives

(57)    Abstract

The present invention relates to a particular form of the (3,5-bis trifluoromethyl)-N-[4- methyl-3-(4-pyridin-3yl

pyrirnidin-2ylamino)-phenyl) -benzamide (formula I), processes for the preparation thereof, pharmaceutical compositions containing this crystal form, and their use as anti tumor agent in humans. The compound of formula I, also known as AN- 019, is: Formula I (I)

(56)    Documents Cited : CAIR M R: "CRYSTALLINE POLYMORPHISM OF ORGANIC COMPOUNDS". TOPIC IN CURRENT

CHEMISTRY SPRINGER BERLIN, DE. vol 198,1 January 1998    WO 2006/027795 A
PAQUETTE, L. (ED)

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