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(11)    Patent No :    AP 2628   
(21)    Application No :    AP/P/2010/005265   
(22)    Filing Date :    10.11.2008   
(24)    Date of Grant &    26.03.2013   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
IT    MI2007A002225    23.11.2007
(84)    Designated State

BW    GM    GH    KE    LS    MW  MZ   NA   SL
SD    SZ    T Z    UG    ZM    ZW
(73) Applicant(s)

ISTITUTO LUSO FARMACO D'ITALIA S.P.A, Via Walter

Tobagi, 8, I-20068, Peschiera Borromeo,
Italy
(72) Inventors
MAGGI Carlo Alberto, Italy
GIULIANI Sandro, Italy
QUARTARA Laura, Italy
et al
(74) Representative
FISHER CORMACK & BOTHA
(51)  International  Classification   A61K 38/08 (2006.01)    A61K 45/06 (2006.01)
(54)    Title

Pharmaceutical compositions containinng bradykinin antagonists and hyaluronic acid, and uses thereof

(57)    Abstract

Disclosed are pharmaceutical compositions containing, as the active ingredients, a mixture of a hyaluronic acid polymer with a bradykinin B2 receptor antagonist. Said compositions have proved especially effective in the treatment of degenerative joint diseases such as osteoarthritis using intra-articular injections

(56)    Documents Cited :    WO 2006/040004 A    GERWIN N et al:    WO 03/103671 A

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