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Back to the List of the Granted Patents                                                Click here to download AP2527 PDF

(11)Patent No :AP 2527

(21)Application No :AP/P/2009/004822

(22)Filing Date :17.10.2007

(24)Date of Grant &06.12.2012

 

(45)Publication : 

 

(30)  Priority Data

(33) Country(31) Number(32) Date

US60/863,60631.10.2006

(84)Designated State 

BWGMGHKELSMW  MZ   NA   SL

SDSZT ZUGZMZW

(73) Applicant(s)

PFIZER PRODUCTS INC., Eastern Point Road, Groton, CT 06340,

United States of America

(72) Inventors

ARHANCET Graciela Barbieri, United States of

America

CHEN Xiangyang, United States of America

HOCKERMAN Susan Landis, United States of

America

et al

(74) Representative

GALLOWAY & COMPANY

ZIMBABWE

 

(51)  International  Classification   C07D 231/54 (2006.01)C07D 401/04 (2006.01)

C07D 405/04 (2006.01)C07D 493/04 (2006.01)

A61K 31/416 (2006.01)A61K 31/4162 (2006.01)

A61P 19/12 (2006.01)

(54)Title 

Pyrazoline compounds as mineralocorticoid receptor antagonists 

(57)Abstract 

Compounds and pharmaceutical!y acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: wherein Rl, R2, R3A, R3B, R4, R5, R6, R7, R8, and X are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, and intermediates are also disclosed 

(56)Documents Cited :WO 98/09969 A   WO 2005/066161 A

 

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