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Back to the List of the Granted Patents                                                Click here to download AP2524 PDF

(11)Patent No :AP 2524

(21)Application No :AP/P/2009/005048

(22)Filing Date :05.05.2008

(24)Date of Grant &04.12.2012

 

(45)Publication : 

 

(30)  Priority Data

(33) Country(31) Number(32) Date

US60/917,33311.05.2007

(84)Designated State 

BWGMGHKELSMW  MZ   NA   SL

SDSZT ZUGZMZW

(73) Applicant(s)

PFIZER INC., 235 East 42nd Street, New York, New York, 10017,

United States of America

 

(72) Inventors

PROULX-LAFRANCE Caroline, United States of

America

VERHOEST Patrick Robert, United States of

America

(74) Representative

GALLOWAY & COMPANY

ZIBABWE

(51)International  Classification   C07D 487/04 (2006.01)

 

(54)Title 

 

Amino-Heterocyclic compounds 

 

(57)Abstract 

 

The invention provides PDE9-inhibiting compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R, R1, R2 and R3 are as defined herein. Pharmaceutical compositions containing the compounds of Formula I, and uses thereof in treating neurodegenerative and cognitive disorders, such as Alzheimer's disease and schizophrenia, are also provided 

 

(56)Documents Cited : FRANK WUNDER, ADRIAN TERSTEEGEN, ANNEGRET REBMANN, CHRISTINA ERB, THOMAS 

 

FAHRING, AND MARTIN HENDRIX

 

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