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(11)    Patent No :    AP 2397   
(21)    Application No :    AP/P/2004/003138   
(22)    Filing Date :    04.04.2003   
(24)    Date of Grant &    23.04.2012   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
DE    102 15 067.2    05.04.2002
DE    102 15 131.8    05.04.2002
(84)    Designated State
GH    KE   T Z   ZM   ZW
(73) Applicant(s)

EURO-CELTIQUE S. A., 2, avenue Charles de Gaulle, Luxembourg 1653,
Luxembourg

(72) Inventors

BRÖGMANN Biance, Germany

MÜHLAU Silke, Germany

SPITZLEY Christof, Germany

et al

(74) Representative

COGHLAN, WELSH & GUEST

ZIMBABWE

(51)  International  Classification   A61K 9/24 (2006.01)    A61K 9/00 (2006.01)
A61K 9/14 (2006.01)   


(54)    Title

Matrix for sustained, invariant and independent release of active compounds.

(57)    Abstract

The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix. whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the

matrix is determined with respect to its substantial release characterristics by ethylcellulose and at least one fatty alcohol. The invention also concerns
(56)    Documents Cited :    EP 0 699 436    EP 0 631 781

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