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(11)    Patent No :    AP 2379   
(21)    Application No :    AP/P/2006/003727   
(22)    Filing Date :    11.03.2005   
(24)    Date of Grant &    08.03.2012   
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/555,623    23.03.2004

(84)    Designated State

GM    GH    KE   LS   MW  MZ   SL   SD   SZ
T Z    UG    ZW

(73) Applicant(s)

PFIZER PRODUCTS INC., Eastern Point Road, Groton, CT 06340,
United States of America
(72) Inventors

BRODNEY Michael Aaron, United States of America

COFFMAN Karen Jean, United States of America

(74) Representative


(51)  International  Classification   C07D 233/38 (2006.01)    C07D 417/14 (2006.01)
(54)    Title

Imidazole compounds for the treatment of neurodegenerative disorders

(57)    Abstract

The present invention relates to compound of the Formula (i) wherein R1, R2, R3, R4, R5, R6, R7 and A are as defined. Compounds of the Formula (I) have activity inhibiting production of A?-peptide. The invention also relates to pharmaceutical compositions and methods for treating diseases and disorders,

for example, neurodegenerative and/or neurological disorders, e.g.,

(56)    Documents Cited :    WO 02/10141 A   WO 00/49037 A


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