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(11)    Patent No :    AP 2377   
(21)    Application No :    AP/P/2009/005089   
(22)    Filing Date :    16.06.2008   
(24)    Date of Grant &    07.03.2012   
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/947,287    29.06.2007
US    61/041,645    02.04.2008
(84)    Designated State

BW    GM  GH   KE   LS   MW  MZ   NA   SL

SD    SZ   T Z   UG   ZM   ZW

(73) Applicant(s)

PFIZER INC., 235 East 42nd Street, New York, New York 10017
United States of America
(72) Inventors
JONES Christopher Scott, United States of America LA GRECA Susan, United States of America

LI Qifang, United States of America et al
(74) Representative
(51)  International  Classification   C07D 401/04 (2006.01)    C07D 403/04 (2006.01)
C07D 401/14 (2006.01)   

(54)    Title

Benzimidazole derivatives

(57)    Abstract

The present invention relates to a compound of the Formula I (I) or a pharmaceutically acceptable salt thereof, wherein Rl, R2, R3A. R3B, R4, R5, X, m, and n are as defined herein. Such novel benzamidazole derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.

(56)    Documents Cited :    WO 2006/124780 A    WO 03/048154 A    WO 2006/050506 A


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