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(11)    Patent No :    AP 2373    (73) Applicant(s)       
(21)    Application No :    AP/P/2007/003888    PFIZER INC., 235 East 42nd Street, New York, NY 10017,       
            United States of America       
                   
(22)    Filing Date :    15.08.2005           
(24)    Date of Grant &    07.03.2012           
                   
(45)    Publication :

(30)  Priority Data    (72) Inventors

    (33) Country    (31) Number    (32) Date    CUI Jingrong Jean, United States of America   
    US            60/605,086    26.08.2004    FUNK Lee Andrew, United States of America   
                           
                        JIA Lei, United States of America   
                        et al       
                        (74) Representative   
(84)    Designated State           
                   
    GM    GH    KE    LS   MW  MZ    SL   SD   SZ    GALLOWAY & COMPANY   
    T Z    UG    ZW            ZIMBABWE       
                               
(51)    International    Classification    C07D 241/20 (2006.01)    C07D 401/12 (2006.01)   
                    C07D 401/14 (2006.01)    C07D 403/04 (2006.01)   
                    C07D 403/14 (2006.01)       

(54)    Title

Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors.

(57)    Abstract

Enantiomerically pure compound of formula (I) are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.
(56)    Documents Cited :    WO 2006/021886 A    WO 2004/076412 A    SAWYER T K: Expert Opinion on investigation

Drugs 2004 UK, Vol.13, No 1, 2004, pp1-19. XP009065998

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