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(11)    Patent No :    AP 2369   
(21)    Application No :    AP/P/2008/004506   
(22)    Filing Date :    12.12.2006   
(24)    Date of Grant &    29.02.2012   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/753,349    21.12.2005
US    60/864,932    08.11.2006


(84)    Designated State

BW    GM  GH   KE   LS   MW  MZ   NA   SL

SD    SZ   T Z   UG   ZM   ZW
 

(73) Applicant(s)

PFIZER PRODUCTS INC., Eastern Point Road, Groton, CT 06340,
United States of America

(72) Inventors

DONG Liming, United States of America

GUO Chuangxing, United States of America

HONG Yufeng, United States of America

et al

(74) Representative

GALLOWAY & COMPANY

ZIMBABWE
(51)    International  Classification   C07D 487/00 (2006.01)
(54)    Title

Carbonylamino pyrrolopyrazoles, potent kinase inhibitors

(57)    Abstract

Carbonylamino Pyrrolopyrazole compounds of formula (I), compositions including these compounds and methods of their use are provided. Preferred compounds of formula (1) have activity as protein kinase inhibitors, including as inhibitors of PAK4.

(56)    Documents Cited :    WO 02/12242 A    WO 2004/056827 A    WO 2005/030776 A

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