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(11)    Patent No :    AP 2324   
(21)    Application No :    AP/P/2006/003558   
(22)    Filing Date :    03.09.2004   
(24)    Date of Grant &    21.11.2011   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/499,723    04.09.2003




(84)    Designated State

BW    GM    GH    KE    LS    MW  MZ   NA   SL
SD    SZ    T Z    UG    ZM    ZW
 

(73) Applicant(s)

CELGENE CORPORATION, 7 Powder Horn Drive, Warren,

07059, New Jersey,
United States of America




(72) Inventors

CHEN Roger, United States of America

MULLER George W, United States of America

JAWORSKY Markian S, United States of America

et al

(74) Representative

FISHER CORMACK & BOTHA
 

(51)  International  Classification   A61K 31/445 (2006.01)    C07D 401/04 (2006.01)

(54)    Title

Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione

(57)    Abstract

Polymorphic forms of 3-(4-amino-1-oxo-1,3

dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of making the polymorphic forms and methods of their use are also disclosed.

(56)    Documents Cited :    US 6,316, 471 B1    J. OF BIO-ORGANIC & MEDICINAL CHEMISTRY LETTERS VOL.9, PGS

1625-1630 (1999)

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