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(11)    Patent No :    AP 2256   
(21)    Application No :    AP/P/2007/004013   
(22)    Filing Date :    02.11.2005   
(24)    Date of Grant &    21.07.2011   
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
ZA    2004/8945    04.11.2004

(84)    Designated State

BW    GM    GH    KE    LS    MW  MZ   NA   SL
SD    SZ    T Z    UG    ZM    ZW

(73) Applicant(s)

SOUTH AFRICAN MEDICAL RESEARCH COUNCIL UNIVERSITY OF CAPE TOWN, Francie van Zijl Avenue, Parow Vallew, 7500 Parrow, South Africa Rondebosch, Cape Town 7700,
South Africa

(72) Inventors

MATSABISA Motlalepula Gilbert, South Africa

CAMPBELL William Ernest, South Africa

FOLB Peter Ian, South Africa

et al

(74) Representative


(51)  International  Classification   A61K36/28 (2006.01)    A61P33/06 (2006.01)
A61K 36/185 (2006.01)   

(54)    Title

Treatment of parasitic infections in humans and animals.

(57)    Abstract

The invention provides a process for the production of a substance or composition for the treatment, by therapy or prophylaxis, of parasitic infections, in particular malarial infections such as Plasrnodium falciparum infections, of the human or animal body. The process comprises extracting the substance or composition from roots of the plant species Dicoma anomala, by an extraction using an organic solvent to obtain a liquid extract containing the substance or composition and removing the solvent from the liquid extract to leave a dried extract containing the substance or composition.

The invention extends also to the use of the substance or composition in the manufacture of a medicament or preparation for such treatment of infections; to a substance or composition for use in such treatment of said infections; to compounds for use in such treatment of said infections; and to a method of

(56)    Documents Cited :    Ramathal et al: PHARMACEUTICAL BIOLOGY, Vol. 39, 2001, PP132-7    Chinemana et al:

JOURNAL OF ETHNOPHARMACOLOGY, Vol.14, 1985, pp 159-172


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