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(11)    Patent No :    AP 2212   
(21)    Application No :    AP/P/2006/003675   
(22)    Filing Date :    29.12.2004   
(24)    Date of Grant &    01.03.2011   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/533,745    30.12.2003
US    60/590,987    26.07.2004
US    60/606,595    01.09.2004

et al

(84)    Designated State

BW    GM  GH   KE   LS   MW  MZ   NA   SL

SD    SZ   T Z   UG   ZM   ZW
 
(73) Applicant(s)

GILEAD SCIENCES, INC., 333 Lakeside Drive, Foster City,

CA 94404,
United States of America

(72) Inventors

CHENG Xiaqin, United States of America

COOK Gary P, United States of America

DESAI Manoj C, United States of America

et al

(74) Representative

HONEY & BLANCKENBERG
 
(51)  International  Classification   A61K31/66 (2006.01)    C07F9/44 (2006.01)

(54)    Title

Phosphonates, Monophosphonamidates, Bisphosphonamidates for the treatment of viral diseases

(57)    Abstract

Compounds and compositions of Formula (I) are described, useful as anti-proliferative agents, and in particular anti-HPV

(56)    Documents Cited : Snoeck et al; Antimalarial Agents and Chemotherapy, Vol. 46, No. 11, Nov 2002, pp 3356-61

US 2003/072814 A1 Christensen et al; Antivairal Agents and Chemotherapy, Vol. 48, 2000, pp

131-42   Keith et al; Antivairal Agents and Chemotherapy, Vol. 47, No. 7, Nov 2003, pp

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