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(11)    Patent No :    AP 2167    (73) Applicant(s)       
(21)    Application No :    AP/P/2007/003955    ZOETIS W LLC, 100 Campus Drive, Florham Park, New       
            Jersey 07932,       
(22)    Filing Date :    06.10.2005    United States of America       
(24)    Date of Grant &    12.11.2010           
(45)    Publication :

(30)    Priority Data                    (72) Inventors   
    (33) Country    (31) Number    (32) Date    PLANA- DURAN Juan, Spain   
    US            60/616,707        07.10.2004    VILA-QUINTANA Rut, Spain   
    US            60/648 459        31.01.2005       
                            TARRES-CALL Jordi, Spain   
                                et al       
                                (74) Representative   
(84)    Designated State                   
    BW    GM    GH    KE    LS    MW    MZ   NA   SL    GILL, GODLONTON & GERRANS   
    SD    SZ    T Z    UG    ZM    ZW        ZIMBABWE       
(51)    International    Classification    A61K 39/145 (2006.01)    A61K 39/295 (2006.01)   
                            A61K 39/39 (2006.01)       

(54)    Title

Multivalent avian influenza vaccines

(57)    Abstract

A vaccine composition and method which is effective in preventing or ameliorating Avian Influenza Virus infection m is set forth herein. The vaccine contains at least two inactivated strains of avian influenza virus, wherein the combined haemoagglutinin (HA) total is at least about 200 HA/dose of the vaccine composition, and wherein each of the strains presents at least about 128 HA/dose, and further wherein one of the strains has the same HA subtype as that of a challenge virus, and wherein at least one of the strains has a different NA subtype than the challenge virus.

(56)    Documents Cited :    FATUNMBI O O ET AL    CAPUA ILARIA ET AL    WO 03/086453    LU XIUHUA ET AL    EP

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