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(11)    Patent No :    AP 2103   
(21)    Application No :    AP/P/2005/003362   
(22)    Filing Date :    23.01.2004   
(24)    Date of Grant &    08.02.2010   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/441,765    23.01.2003

(84)    Designated State

BW    GM    GH    KE    LS    MW  MZ   NA   SL
SD    SZ    T Z    UG    ZM    ZW
 

(73) Applicant(s)

SHIRE HOLDINGS AG, Bundersstrasse 5, Zug 6300,

Switzerland


(72) Inventors

FRANKLIN Richard, United Kingdom

(74) Representative

HONEY & BLANCKENBERG
 

(51)  International  Classification   A61K 9/70 (2006.01)    A61K 31/517 (2006.01)


(54)    Title

A skin permeable form of anagrelide and device therefore

(57)    Abstract

The present invention provides a method for the treatment or prevention of thrombocythemia in a patient comprising administering to said patient an effective amount of anagrelide, anagrelide in base form, or a pharmaceutically
acceptable salt of anagrelide in a manner whereby first pass liver metabolism

(56)    Documents Cited :    Storen,Et -al    WO 93/09794 A    US 5 306 709 A

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