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(11)    Patent No :    AP 2083   
(21)    Application No :    AP/P/2006/003661   
(22)    Filing Date :    17.12.2004   
(24)    Date of Grant &    04.01.2010   
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/530,525    17.12.2003
US    10/783,459    20.02.2004

(84)    Designated State

BW    GM  GH   KE   LS   MW  MZ   NA   SL

SD    SZ   T Z   UG   ZM   ZW

(73) Applicant(s)

MERIAL LIMITED, 3239 Satellite Boulevard, Duluth, GA 30096,
United States of America

(72) Inventors

BOECKH Albert, United States of America CRAMER Luiz Gustavo, United States of America SOLL Mark D., United States of America

et al

(74) Representative


(51)  International  Classification   A01N 43/56 (2006.01)    A01N 47/02 (2006.01)

(54)    Title

Topical formulations comprising a 1-N-arylprazole derivative and a formamidine

(57)    Abstract

The present invention provides for, inter alia, novel topical formulations comprising at least one 1 -N-arypyrazole derivative and a formamidine such as arnitraz and to methods for treating, controlling or preventing parasite infestations on mammals or birds. The inventive formulations include spot-on, pour-on or spray formulations and may include further ectoparasilicide, such as an IGR compound, an avermectin or milbemycin derivative, or a pyrethroid insecticide, and/or anthelmintics such as benzimidazoles or imidazolthiazoles. The inventive formulation provides a larger duration of parasite control at a faster rate of control. The inventive formula remains effective up to three months from the first application. Moreover, the inventive formulations prevent tick attachment to the animal, thereby providing protection against tick borne diseases. The ectoparasites which may be controlled, treated or prevented by the present invention includes ticks, flea, mites, mange, lice, mosquitoes, flies and cattle grubs.
(56)  Documents Cited :    US 6 538 013 B2


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