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(11)    Patent No :    AP 2004   
(21)    Application No :    AP/P/2002/002457   
(22)    Filing Date :    14.09.2000   
(24)    Date of Grant &    10.06.2009   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
GB    9922963.5    28.09.1999

(84)    Designated State

GM    GH    KE    LS   MW  MZ   SL   SD   SZ
T Z    UG    ZM    ZW

(73) Applicant(s)

PFIZER INC., 235 East 42nd Street , New York, New York 10017,
United States of America

(72) Inventors

BENTLEY Authur, United Kingdom

HOWARD-FIELD Simon Arnold, United Kingdom

OGILVIE Roland James, United States of America

et al

(74) Representative

GALLOWAY & COMPANY
 

(51)  International  Classification   A61K 9/08 (2006.01)    A61K 9/20 (2006.01)
A61K 31/404 (2006.01)   


(54)    Title

Polymorphic salt as an anti-migraine drug.

(57)    Abstract

The present invention is concerned with a crystalline, polymorphic form of a compound of formula (I) characterised by a powder X-ray diffraction pattern obtained using copper k-alpha1 (y=0.15046nm) which shows main peaks at 9.28, 10.38, 11.37, 12.40, 16.84, 17.46,17.53, 17.78, 17,98, 19.48, 20.70, 21.29, 21.45, 22.21`, 22.64, 23.08, 25.20, and 25.79. The invention also relates to processes for the preparation of said form, to pharmaceutical compositions containing same and to its use in medicine, particularly the treatment of conditions for which an agonist of 5 -HT1 receptors is indicated, for example, migraine.

(56)    Documents Cited :    WO 99 01135 A    WO 96 06842 A

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