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(11)    Patent No :    AP 1965   
(21)    Application No :    AP/P/2002/002663   
(22)    Filing Date :    09.05.2001   
(24)    Date of Grant &    04.03.2009   
           
(45)    Publication :

(30)    Priority Data

(33) Country    (31) Number    (32) Date
GB            0015835.2    27.06.2000
GB            0014046.7    26.05.2000
   
(84)  Designated State   
GM    GH    KE    LS   MW  MZ    SL   SD   SZ
T Z    UG    ZW       
 
(73) Applicant(s)

PFIZER INC., 235 East 42nd Street , New York, New York 10017,
United States of America

(72) Inventors

PERROS Manoussos, United Kingdom

PRICE David Anthony, United Kingdom

STAMMEN Blanda Luzia Christa, United Kingdom

et al

(74) Representative

GALLOWAY & COMPANY
 

(51)  International  Classification   A61K 31/4196 (2006.01)    A61K 31/46 (2006.01)
A61P 1/04 (2006.01)   


(54)    Title

Tropane derivatives useful in therapy.

(57)    Abstract

The present invention provides compounds of the formula (I): wherein R1 is C3-6 cycloalkyl optionally substituted by one or more fluorine atoms, or C1 -6, alkyl optionally substituted by one or more fluorine atoms, or C3-6 cycloalkylmethyl optionally ring-substituted by one or more fluorine atoms; and R2 is phenyl optionally substituted by one or more fluorine atoms, to pharmaceutically acceptable salts and solvates thereof, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such compounds.

(56)  Documents Cited :    WO 98 25617 A

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