slide 1

Back to the List of the Granted Patents                                                Click here to download AP1958 PDF

(11)    Patent No :    AP 1958   
(21)    Application No :    AP/P/2004/003088   
(22)    Filing Date :    23.12.2002   
(24)    Date of Grant &    20.02.2009   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
IT    RM2001A000767    24.12.2001

(84)    Designated State

GM    GH    KE    LS   MW  MZ   SL   SD   SZ
T Z    UG    ZM    ZW
 

(73) Applicant(s)

ISTITUTO SUPERIORE DI SANITA, Viale Regina Elena 299,

I-00161 Rome,
Italy

(72) Inventors

SPADAFORA Corrado, Italy

LAVIA Patrizia, Italy

MATTEI Elisabetta, Italy

et al

(74) Representative

FISHER CORMACK & BOTHA
 

(51)  International  Classification   A61K    31/535 (2006.01)    A61K 31/495 (2006.01)
A61K    31/57 (2006.01)   


(54)    Title

Non-nucleosidic inhibitors of reverse transcriptase as antagonists of cell proliferation and inducers of cell differentiation

(57)    Abstract

The invention refers to the use of Reverse Transcriptase (RT) inhibitor compounds for the preparation of pharmaceutical compositions to counteract the loss of cellular differentiation in tumour and non tumour pathologies, said compound being able to bind the hydrophobic pocket on the RT subunit p66. Particularly preferred for such uses are the following compounds: nevirapine, efavirenz, delavirdine, corresponding salts and/or pharmaceutically acceptable derivatives thereof.


(56)    Documents Cited :    Shaw A.J. et al    Grimaudo S. et al    US 6 258 839 A    Ghori A et al

Newsletter

Join our newsletter for CIPIT news through subscriptions!

SEND

Social Media

    

Contact Us

TEL : (254) 703 034 612