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(11)    Patent No :    AP 2741   
(21)    Application No :    AP/P/2008/004323   
(22)    Filing Date :    29.06.2006   
(24)    Date of Grant &    04.09.2013   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/697,067    05.07.2007
(84)    Designated State

BW    GM    GH    KE    LS    MW  MZ   NA   SL
SD    SZ    T Z    UG    ZM    ZW
(73) Applicant(s)

THE REGENTS  OF THE UNIVERSITY OF CALIFORNIA,

1111 Franklin Street, 12th Floor, Oakland, 94607-5200,
California,

United States of America
(72) Inventors

RO Dae- Kyun, Canada

PARADISE Eric M, United States of America

NEWMAN Karyn, United States of America

et al

(74) Representative

FISHER CORMACK & BOTHA
 

(51)    International  Classification   A61K 51/00 (2006.01)
(54)    Title

Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
(57)    Abstract

The present invention provides isolated nucleic acids comprising nucleotide sequences encoding isoprenoid modifying enzymes, as well as recombinant vectors comprising the nucleic acids. The present invention further provides genetically modified host cells comprising a subject nucleic acid or recombinant vector. The present invention further provides a transgenic plant comprising a subject nucleic acid. The present invention further provides methods of producing an isoprenoid compound, the method generally involving culturing a subject genetically modified host cell under conditions that permit synthesis of an isoprenoid compound modifying enzyme encoded by a subject nucleic acid.

(56)    Documents Cited :    US 2004/162420 A1    LUPIEN S et al    WO 98/59042 A    EP 1354955 A    BERTEA C M et

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