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(11)    Patent No :    AP 2710   
(21)    Application No :    AP/P/2009/004790   
(22)    Filing Date :    03.09.2007   
(24)    Date of Grant &    30.07.2013   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/845,065    15.09.2006
US    60/947,852    03.07.2007
US    60/952,628    30.07.2007
et al

(84)    Designated State

BW    GM  GH   KE   LS   MW  MZ   NA   SL

SD    SZ   T Z   UG   ZM   ZW
(73) Applicant(s)
PFIZER PRODUCTS INC., Eastern Point Road, Groton, CT 06340,
United States of America
(72) Inventors

BHUMRALKAR Dilip, United States of America CHENG Hengmiao, United States of America DRESS Klaus, Ruprecht, United States of America et al

(74) Representative

GALLOWAY & COMPAN
ZIMBABWE
(51)  International  Classification   C07D 471/04 (2006.01)    A61P 35/00 (2006.01)
A61K 31/519 (2006.01)   


(54)    Title

Pyrido (2, 3-D) Pyrimidinone compounds and their use as P13 inhibitors

(57)    Abstract

The present invention is directed to novel 4-methylpyridopyhmidinone compounds of Formula (I) and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3- Ka).

(56)    Documents Cited :    US 2004/009993 A1    WO 2005 105801 A

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