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(11)    Patent No :    AP 2696   
(21)    Application No :    AP/P/2004/003042   
(22)    Filing Date :    31.10.2002   
(24)    Date of Grant &    17.07.2013   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
ZA    2001/8978    31.10.2001
(84)    Designated State

KE    LS   MW  MZ   SZ   TZ   UG   ZM  Z
(73) Applicant(s)

THE SOUTH AFRICAN MEDICAL RESEARCH COUNCIL,

Fransie Van Zijl Drive, Parrowvallei, 7505 Cape Town,
South Africa

UNIVERSITY OF CAPE TOWN, Lovers  Walk, Rondebosch,
7701 Cape Town,

South Africa

(72) Inventors

WILLIAMSON Carolyn, South Africa

VAN HARMELEN Joanne Heidi, South Africa

RAY Clive Maurice, South Africa
et al
(74) Representative

FISHER CORMACK & BOTHA
(51)  Intern ational  Classification   C07K 14/16 (2006.01)    C12N 15/49 (2006.01
(54)    Title
HIV-1 subtype isolate regulatory/accessory genes, and  modifications and derivatives thereof.

(57)    Abstract

The invention describes HIV- 1 subtype isolate regulatory/accessory genes, and modifications and derivatives thereof. The genes which are described are the tat, nef and rev genes. Consensus amino acid sequences are also disclosed. The invention also relates to a vaccine including two or more of the nucleotide sequences, and nucleotide sequences from the pol and/or gag genes of HIV -1.
(56)    Documents Cited :    HARVARD AIDS INSTITUTE    WO 02 04493 A    WO 02 04494 A    NOVITSSKY V et al.

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