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(11)    Patent No :    AP 2655   
(21)    Application No :    AP/P/2008/004390   
(22)    Filing Date :    22.09.2006   
(24)    Date of Grant &    07.05.2013   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/720,257    22.09.2005
(84)    Designated State

BW    GM    GH    KE    LS    MW  MZ   NA   SL
SD    SZ    T Z    UG    ZM    ZW

(73) Applicant(s)

INTERMUNE , INC., 3280 Bayshore Boulevard, Brisbane,

California 94005,
United States of America

(72) Inventors

RADHAKRISHNAN Ramachandran, United States of

America

VLADYKA Ronald, United States of America

SULTZBAUGH Kenneth, United States of America

et al
(74) Representative

FISHER CORMACK & BOTHA
 

(51)  International  Classification   A61K    9/48    92006.01)    A61K 9/28 (2006.01)
A61K    9/16    (2006.01)   


(54)    Title

Capsule formulation of pirfenidone and pharmaceutically acceptable excipients

(57)    Abstract

A capsule formulation of pirfenidone is provided that includes pharmaceutically acceptable excipients. In one embodiment, this capsule formulation is capable of sustaining desirable pharmacokinetic responses in a patient. Further provided are methods of treating fibrotic conditions and other cytokine-mediated disorders by administering pirfenidone capsules of such formulation to a patient in need.

(56)    Documents Cited :    EP 1 356 816 A1    WO 94/26249 A    EP 0 383 591 A2    WO 97/10712 A

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