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(11)    Patent No :    AP 2629   
(21)    Application No :    AP/P/2007/003899   
(22)    Filing Date :    27.07.2005   
(24)    Date of Grant &    28.03.2013   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/591,811    27.07.2004

(84)    Designated State
BW    GM    GH    KE    LS    MW  MZ   NA   SL
SD    SZ    T Z    UG    ZM    ZW

(73) Applicant(s)

GILEAD SCIENCES, INC., 333 Lakeside Drive, Foster City,

CA 94404,
United States of America
(72) Inventors

BOOJAMRA Constantine G, United States of

America

LIN Kuei-Ying, United States of America

MACKMAN Richard L, United States of America

e al
(74) Representative
HONEY & BLANCKENBERG
(51)  International  Classification   A61K 31/662 (2006.01)    A61K 47/48 (2006.01)
C07F 9/02 (2006.01)   
(54)    Title

Nucleoside phosphonate conjugates as anti HIV agents.

(57)    Abstract

The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

(56)  Documents Cited :    PARANG K et al    WO 03/090690 A    SHIROKOVA E. A:    WO 91/19721 A    WO
    92/00988 A               
    WO 93/24510 A    WO 03/091264 A    RU 2 106 353 C    RU 2 188 203 C    SIDDIQUI A Q

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