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(11)    Patent No :    AP 2617   
(21)    Application No :    AP/P/2007/004178   
(22)    Filing Date :    04.04.2006   
(24)    Date of Grant &    18.03.2013   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
EP    05102616.9    04.04.200
(84)    Designated State

BW    GM    GH    KE    LS    MW  MZ   NA   SL
SD    SZ    T Z    UG    ZM    ZW

(73) Applicant(s)

TIBOTEC PHARMACEUTICALS LTD., Eastgate Village,

Eastgate, Little Island, Co Cork,
Ireland
(72) Inventors
BAERT Lieven Elvire Colette, Belgium
LEWI Paulus Joannes, Belgium
HEERES Jan, Belgium
et al
(74) Representative
HONEY & BLANCKENBERG
(51)  International  Classification   A61K 47/10 (2006.01)    A61K    47/16 (2006.01)
A61P 31/18 (2006.01)    A61K    31/505 (2006.01)
(54)    Title

Prevention of HIV-infection

(57)    Abstract

This invention relates to the use of a parenteral formulation comprising the NNRTI TMC278 for the long term prevention of HIV infection in a subject at risk of being infected by HIV which comprises the intermittent administration of the said formulation at long time intervals.

(56)    Documents Cited :    WO 2005/021001 A   JANSSEN P A et al: vol. 48, no, 6 November 2004, pages 1901-1909,

XP008050052, issn: 0022-2623    SUSMAN E: "retroviruses and opprtunistic infections-12th
conference. 22-25th 2005, Boston, MA, USA

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