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(11)    Patent No :    AP 1944   
(21)    Application No :    AP/P/2001/002060   
(22)    Filing Date :    22.06.1999   
(24)    Date of Grant &    02.02.2009   
           
(45)    Publication :

(30)  Priority Data       
(33) Country    (31) Number    (32) Date
US    60/091,403    29.06.1998

(84)    Designated State

GM    GH   KE   LS   MW  SL   SD   SZ   UG

ZW

(73) Applicant(s)

U.S. MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES, Dept. of the Army, 504 Scott Street, Frederick, MD 21702,

United States of America



(72) Inventors

HART Mary Katherine, United States of America

WILSON Julie A, United States of America

PUSHKO Peter, United States of America

et al

(74) Representative

FISHER CORMACK & BOTHA
 

(51)    International  Classification   C12N 15/40 (2006.01)    C12N 7/01 (2006.01)
    C07K 14/00 (2006.01)    C07K 16/08 (2006.01)
    C12Q 1/68 (2006.01)    G01N 33/569 (2006.01)
    G01N 33/577 (2006.01)    A61K 39/12 (2006.01)
    A61K 31/7105 (2006.01)   
(54)    Title   

Ebola viron proteins expressed from venezuelan equine encephalitis (Vee) virus replicons.

(57)    Abstract

Using the ebola GP, NP, VP24, VP30, VP35 and VP40 virion proteins, a method and composition for use in inducing an immune response which is protective against infection with ebola virus described.

(56)    Documents Cited :    WO 96 37616 A    L. XU et al; Nature Medicine, Vol. 4, no.1;  01/1998, pp37-42    L.

Vanderzanden et al; Virology, Vol.246 No. 1, Academic Press, Inc., NY. US.

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